Vitamin D supply of the mother-placenta-newborn triad in the Arctic zone of Russia
Neonatology: News, Opinions, Training]. 2025; 13 (2): 26–32. DOI: https://doi.org/10.33029/2308-2402-2025-13-2-26-32 (in Russian)
Maria A. Chebargina, Olga A. Senkevich, Yuri G. Kovalsky, Mikhail V. Gorokhovsky
Vitamin D status during pregnancy is important for maternal health, fetal skeletal growth, and optimal pregnancy outcomes.
Objective – to assess the level of vitamin D supply of the “mother – placenta – newborn” triad in the Arctic zone of the Far Eastern Federal District.
Material and methods. Study design: observational, analytical, cross-sectional. To assess the distribution of vitamin D content in the dynamic system “mother–placenta–fetus (newborn)”. Analysis of the concentration of calcidiol in each link of the system was carried out. Using the random sampling method, 30 triads “mother–placenta–newborn” were included in the main study group (Arctic zone, Anadyr) that were characterized by the physiological course of the perinatal period. The control group of the study (Southern zone, Khabarovsk) included 54 triads.
Results. Concentration of 25(OH)D in the blood serum of mothers was in 1.5 times lower than in newborns (10.0 vs 14.6 ng/ml; p=0.003) and in placentas (14.3 ng/ml, p=0.006). The vitamin D supply in the subgroups of newborns and placentas did not have statistically significant differences. 100.0% of mothers had vitamin D deficiency. Predominant of severe deficiency in comparison with the subgroups of newborns and placentas, respectively (p=0.031 vs p=0.005). Vitamin D deficiency and insufficiency in mothers of the main study group were diagnosed 8 and 3 times more often in comparison with the southern group (OR=8.000; 95% CI 2.636–24.279 and OR=2.857; 95% CI 1.117–7.311) respectively. The prevalence of low vitamin D status in the subgroup of newborns was 72 times higher in the Arctic zone compared with the southern group (OR=72.000; 95% CI 16.655–311.252).
Conclusion. It was found that pregnant women and newborns from the Arctic zone of Russia are an extremely vulnerable group of the population due to the climatic and geographical features of the territory.
Some relevant items in VitaminDWiki
- Dr. Hollis interview on the importance of Vitamin D during pregnancy - Feb 2025
- Consensus: Vitamin D is the most needed supplement before, during, and after pregnancy - Jan 2025
- Russia and Vitamin D - many studies
- The top 10 chronic childhood health problems are all associated with low Vitamin D
- Children with low vitamin D became adults having 2X more chronic health problems – Nov 2024
- Neonate loading dose of 30,000 IU vitamin D helped a lot – May 2014
"Happy" Northern Finland has learned to fortifiy and supplement (vs sad Arctic Russians
- Happiest country on earth has a high Vitamin D level (Finland, with little sun) – March 2022
- After years of vitamin D fortification and supplementation, Finland has 38 ng levels - March 2022
- Stillbirth rates dropped from 4.1% to 2.8% as Finland increased Vitamin D fortification – May 2022
- 95 percent of pregnant women in Finland took vitamin D – PHD Dissertation Dec 2019