Proxy measures of vitamin D status - season and latitude - correlate with adverse outcomes after bariatric surgery in the Nationwide Inpatient Sample, 2001-2010: a retrospective cohort study.
Obes Sci Pract. 2015 Dec;1(2):88-96. Epub 2015 Dec 14.
Peterson LA1, Canner JK2, Cheskin LJ3, Prokopowicz GP4, Schweitzer MA5, Magnuson TH5, Steele KE5.
1The Johns Hopkins Center for Bariatric SurgeryBaltimoreUSA; The Johns Hopkins Bloomberg School of Public HealthBaltimoreUSA.
2The Johns Hopkins Center for Surgical Trials and Outcomes Research Baltimore USA.
3The Johns Hopkins Bloomberg School of Public HealthBaltimoreUSA; The Johns Hopkins Weight Management CenterBaltimoreUSA; The Global Obesity Prevention Center at Johns HopkinsBaltimoreUSA.
4The Johns Hopkins Outpatient Center Baltimore USA.
5The Johns Hopkins Center for Bariatric Surgery Baltimore USA.
Bariatric Surgery (US) - Winter and high latitude associated with longer stay (> 3 days) and various complications
See also VitaminDWiki
- Prior to Bariatric Surgery 96 percent were vitamin D deficient – July 2014
- Virtually all Bariatric Surgery patients vitamin D deficient – should we routinely supplement – Jan 2011 YES!!
- 50,000 IU of dry vitamin D needed at least daily following obesity surgery – forum Jan 2016 Bio-Tech brand
- 11 years after Gastric Bypass Surgery vitamin D still low – Oct 2013
- Search VitaminDWiki for "bariatric surgery" OR "gastric bypass" 129 items as of Oct 2016
- Gastric bypass reduces vitamin D by at least 25 percent – Feb 2011
- Gut-Friendly Vitamin D a form of vitamin D made for poor guts
- Gastric bypass reduces vitamin D by at least 25 percent – Feb 2011
- 17 percent more heart attacks in the winter (perhaps due to low vitamin D) – July 2018
- Bariatric Surgery is Bad for the Bone (reduce vitamin uptake, etc)– 2016
- Overview Deficiency of vitamin D has a chart - a portion of which shows the problems AFTER Bariatric surgery
Latitude
Overview Gut and vitamin D contains the following summary
- Gut problems result in reduced absorption of Vitamin D, Magnesium, etc.
- Celiac disease has a strong genetic component.
- Most, but not all, people with celiac disease have a gene variant.
- An adequate level vitamin D seems to decrease the probability of getting celiac disease.
- Celiac disease causes poor absorption of nutrients such as vitamin D.
- Bringing the blood level of vitamin D back to normal in patients with celiac disease decreases symptoms.
- The prevalence of celiac disease, not just its diagnosis, has increased 4X in the past 30 years, similar to the increase in Vitamin D deficiency.
- Review in Nov 2013 found that Vitamin D helped
Many intervention clinical trials with vitamin D for Gut problems (101 trials listed as of Sept 2019) - All items in category gut and vitamin D
207 items
Overview Obesity and Vitamin D contains the following summary- FACT: People who are obese have less vitamin D in their blood
- FACT: Obese need a higher dose of vitamin D to get to the same level of vit D
- FACT: When obese people lose weight the vitamin D level in their blood increases
- FACT: Adding Calcium, perhaps in the form of fortified milk, often reduces weight
- FACT: 168 trials for vitamin D intervention of obesity as of Dec 2021
- FACT: Less weight gain by senior women with > 30 ng of vitamin D
- FACT: Dieters lost additional 5 lbs if vitamin D supplementation got them above 32 ng - RCT
- FACT: Obese lost 3X more weight by adding $10 of Vitamin D
- FACT: Those with darker skins were more likely to be obese Sept 2014
- OBSERVATION: Low Vitamin D while pregnancy ==> more obese child and adult
- OBSERVATION: Many mammals had evolved to add fat and vitamin D in the autumn
- and lose both in the Spring - unfortunately humans have forgotten to lose the fat in the Spring
- SPECULATION: Low vitamin D might be one of the causes of obesity – several studies
- SUGGESTION: Probably need more than 4,000 IU to lose weight if very low on vitamin D due to
risk factors such as overweight, age, dark skin, live far from equator,shut-in, etc. - Obesity category has
441 items See also: Weight loss and Vitamin D - many studies Child Obesity and Vitamin D - many studies Obesity, Virus, and Vitamin D - many studies
Obese need more Vitamin D- Normal weight Obese (50 ng = 125 nanomole)
Obese need 2X to 3X more vitamin D - Nov 2014 has the following
See also web
Bariatric surgery and vitamin D: key messages for surgeons and clinicians before and after bariatric surgery - June 2016
Publisher wants £85 for the PDFDownload the PDF from VitaminDWiki
North South Length of stay >3d 43% 32%
Wounds vs seasonWounds vs latitude
OBJECTIVE:
To investigate the association between adverse surgical outcomes following bariatric surgery and proxy measures of vitamin D (VitD) status (season and latitude) in the Nationwide Inpatient Sample (NIS).
BACKGROUND:
Obesity is an independent risk factor for VitD deficiency (25(OH)D < 20 ng ml-1). VitD deficiency compounds the chronic inflammation of obesity, increasing the risk of adverse outcomes following bariatric surgery. Epidemiology has long used season and latitude as proxies for group VitD, as VitD status is largely determined by sun exposure, which is greatest during summer and at the Equator.
METHODS:
We assessed proxy measures of group VitD status. We compared surgeries in VitD Summer (July to September), Winter (January to March), and Fall/Spring (October to December and April to June) and in the North (=37°N) vs. the South (<37°N).
RESULTS:
We identified 932,091 bariatric surgeries; 81.2% were women and 74.4% were white. Sex was unequally distributed by season (p = 0.005). Median age was 43.0 years (all groups). Most surgeries occurred in the North (64.8%). Adverse outcome rates ranged from 0.01% (wound infections) to 39.4% [prolonged length of stay {LOS}]. Season was inversely associated with wound infection (p = 0.018) and dehiscence (p = 0.001). Extended LOS was inversely correlated with season (p < 0.001). These relationships held after adjustment. Prolonged LOS (p < 0.001) and any complication (p = 0.108) were more common in the North.
CONCLUSIONS:
We have demonstrated a graded relationship between seasonality and adverse outcomes following bariatric surgery. The association was strongest for dehiscence and prolonged LOS. These relationships held when using latitude. A prospective study measuring pre-operative 25(OH)D concentration would strengthen the case for causality in adverse surgical outcomes.PMID: 27774252 DOI: 10.1002/osp4.15
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