- People with high levels of Vitamin D are 25% less likely to get bladder cancer
- Some cancers have have been proven to be prevented or treated by Vitamin D
- Vitamin D has not yet been proven to treat bladder cancer.
- However Vitamin D does relieve pain and reduce the amount of chemotherapy needed
(More bladder cancer info below:28 studies ) Learn how Vitamin D is essential for good health
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COVID-19 treated by Vitamin D - studies, reports, videos- Bladder Cancer – June 2022
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6 Meta-anayses of Bladder Cancer - All Bladder Cancer studies in VitaminDWiki
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Bladder Cancer – June 2022
A prospective trial investigating the role of Serum 25-Hydroxyvitamin D in diagnosis and prognosis of bladder cancer
PLOS x Published: June 16, 2022 https://doi.org/10.1371/journal.pone.0266371
Ahmed Abdelgawad ,Abdelwahab Hashem,Ahmed Mosbah ,Laila A. Eissa
Purpose
Higher levels of serum 25-hydroxyvitamin D 25(OHD) are associated with better prognosis in breast and colorectal cancer. However, the evidence is still inconclusive for bladder cancer (BC). Herein, we investigated the diagnosis and prognosis roles of serum levels of 25(OHD) in suspected BC patients presented by hematuria.Methods
This prospective cohort study involved suspected patients of BC presented with hematuria. Patients were evaluated by CT urogram, office cystoscopy and urine cytology with subsequent inpatient biopsy for positive findings. Baseline blood samples were collected for measurement of 25(OHD) by electrochemiluminescence binding assay at the time of diagnosis. Patients with non-muscle-invasive BC (NMIBC) underwent transurethral resection of bladder tumor (TURBT) and adjuvant intravesical chemotherapy or BCG instillation. Patients were followed up for their recurrence status during 10 to 24 months. Recurrence was defined as the first time of NMIBC pathological relapse during the follow up period.Results
A total of 115 patients were included in the final analysis. Patients had proven pathological BC (64 with NMIBC, and 20 with muscle invasive) and 31 patients were considered as control group. Controls were those patients with BC-free workup (including cytology, cystoscopy, and upper tract imaging). BC group showed a lower level of 25(OHD) than control group 16.47±5.88 versus 28.99±3.19 ng/mL (p<0.001). In addition, muscle invasive group also showed a lower level than NMIBC group 13.17±4.5 versus 17.49±5.04 ng/mL (P = 0.003). During the follow-up period of, tumor recurrence occurred in 16 (25%) of NMIBC patients. The baseline 25(OHD) were decreased in patients who experienced early recurrence; without being statistically significant (15.99 ± 5.17 vs. 18.38 ± 5.14 ng/mL; p = 0.08). 25(OHD) deficiency/insufficiency occurred in 5 (16.1%) and 64 (76.2%) in control and BC patients, respectively, (odds-ratios (OR): 2.13; 95% confidence intervals (CI), 1.52–2.99; P < 0.0001).Conclusion
Serum 25(OHD) is significantly decreased in BC patients especially those with tumor muscle invasive group. However, the baseline serum 25(OHD) does not predict the recurrence in the NMIBC patients.
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6 Meta-anayses of Bladder Cancer This list is automatically updated
- Bladder cancer in muscles 2.7 times more-likely if vitamin D less than 20 ng -meta-analysis May 2024
- Deaths from many types of Cancer associated with low vitamin D- review of meta-analyses Sept 2020
- Bladder cancer modifiable risk factors include low vitamin D – meta-analysis March 2016
- Bladder cancer 60 percent less likely if have high vitamin D – meta-analysis Dec 2015
- Bladder cancer 25 percent less likely if have high vitamin D – meta-analysis April 2015
- Bladder cancer 25 percent less likely if have high vitamin D – meta-analysis Oct 2014
All Bladder Cancer studies in VitaminDWiki
- wiki page:
- Bladder cancer in muscles 2.7 times more-likely if vitamin D less than 20 ng -meta-analysis May 2024
- Cancers are sometimes associated with poor CYP24A1 gene (Vitamin D) (Bladder Cancer in this case) – April 2024
- 13 Cancers are helped by Vitamin D – Biobank July 2023
- Deaths from many types of Cancer associated with low vitamin D- review of meta-analyses Sept 2020
- Bladder Cancer deaths – 2.9X more likely if low Vitamin D, no death if more than 30 ng – July 2020
- Good Vitamin D receptor reduced bladder cancer and cisplatin deaths – April 2019
- Increased incidence of 7 cancers if live far from equator (if not take vitamin D) – March 2019
- Urinary Bladder Cancer survival is associated with vitamin D receptor: 14 months vs 53 months – Oct 2015
- Bladder cancer modifiable risk factors include low vitamin D – meta-analysis March 2016
- Bladder cancer 60 percent less likely if have high vitamin D – meta-analysis Dec 2015
- Poor Bladder Cancer survival associated with poor Vitamin D receptor – Oct 2015
- Bladder cancer 25 percent less likely if have high vitamin D – meta-analysis April 2015
- Bladder cancer 25 percent less likely if have high vitamin D – meta-analysis Oct 2014
- Off Topic: Cannabinoids as Cancer chemotherapy – Sept 2014
- Molecular Link between Vitamin D and Cancer Prevention – Oct 2013
- Higher levels of Vitamin D assocated with bladder cancer survival by veterans – Feb 2013
- Free vitamin D (VDR) may be more important than total for bladder cancer – March 2013
- Hypothesis: Vitamin D or UV will decrease bladder cancer – Feb 2013
- Vitamin D and Risk of Rarer Cancers – Jan 2013
- 80 percent more likely to have bladder cancer if have low level of vitamin D – Oct 2012
- Cancer - Bladder
- Bladder Cancer, Vitamin D, and Fibroblast Growth Factor – Oct 2012
- Getting little UV is associated with 15 types of Cancer – Jan 2012
- Less than 20 ng of Vitamin D increases bladder cancer by 70 percent – Oct 2010
- China has documented that less UV results in more cancer – June 2010
- 1200 IU of vitamin D did not have any impact on bladder cancer – June 2010
See also All items in category Cancer and Vitamin D292 items
See also web
- Vitamin D and Vitamin D-binding protein and risk of bladder cancer: A nested case-control study in the Norwegian Janus Serum Bank Cohort - June 2021 PDF
- Low Plasma 25-Hydoxyvitamin D at Diagnosis Predicts Poor Outcomes in Patients with Bladder Cancer: A Prospective Cohort Study - July 2020 https://doi.org/10.1080/01635581.2020.1737150
- 5 out of 7 studies of Bladder Cancer and Vitamin D found an association Science Daily Nov 2016
- LOW SERUM 25-HYDROXYVITAMIN D IS ASSOCIATED WITH INCREASED BLADDER CANCER RISK: A SYSTEMATIC REVIEW AND EVIDENCE OF A POTENTIAL MECHANISM - Jan 2019;
"Low vitamin D levels were associated with bladder cancer risk in 5/6 of the studies"
Bladder cells appear to need to activate Vitamin D locally, doi: 10.1016/j.jsbmb.2019.01.002
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