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Bone mineral density improvement by Vitamin D plus fluoride is augmented by laser acupuncture – RCT March 2023

Effect of laser acupuncture on pain and density of bone in osteoporotic postmenopausal women: a randomized controlled trial

Menopause. 2023 Mar 21. doi: 10.1097/GME.0000000000002166 Behind Paywall
Elham S Hassan 1, Ahmed Mohamed Maged 2, Amal Kotb 3, Mona Fouad 2, Noura El-Nassery 2, Wafaa M Kamal 4

Objective: This study aimed to evaluate the value of laser acupuncture (LA) on forearm bone mineral density (BMD) and wrist pain in osteoporotic postmenopausal women.

Methods: Sixty-eight postmenopausal women diagnosed with osteoporosis were randomly allocated equally to one of two sets. The drug-only group received calcium and vitamin D3 supplement containing fluoride daily for 12 weeks, whereas the drug/LA group received LA therapy for 20 minutes per session, three sessions weekly, in addition to the same supplementation. The primary outcome parameter was assessment of BMD of the nondominant arm. Other outcomes included wrist pain.

Results: There was a highly significant improvement in the
T-score of forearm BMD in both groups

  • -2.844 ± 0.476 to -2.597 ± 0.478 and
  • -2.944 ± 0.486 to -1.652 ± 0.728 in the drug-only and drug/LA groups, respectively; P < 0.0001) and

visual analog scale score (

  • 7.50 ± 0.79 to 4.24 ± 1.07 and
  • 7.24 ± 0.82 to 3.09 ± 0.75 in the drug-only and drug/LA group, respectively; P < 0.0001).

The improvement of both BMD and pain score was significantly higher in the drug/LA group (-1.303 and 4.15) compared with the drug-only group (-0.247 and 3.26; P < 0.0001).

Conclusions: LA in combination with calcium and vitamin D supplementation containing fluoride is an effective modality in improving forearm BMD and reducing pain in osteoporotic postmenopausal women.

Founder of VitaminDWiki designed, built and has been using LLLT

for 13 years for a variety of health problems for his wife and himself

9+ VitaminDWiki pages with LOW LEVEL LASER OR LLLT in title

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Examples of istudies ncreasing bone in VitaminDWiki

26+ VitaminDWiki pages with BONE MINERAL DENSITY or BMD in title

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Items found: 29
Title Modified
Vitamin D during pregnancy increased child’s bone mineral density – meta-analysis April 2023 27 Apr, 2023
Bone Mineral Density and Vitamin D - many studies 13 Apr, 2023
Transgender associated with autism, low vitamin D, low BMD, etc. - many studies 05 Apr, 2023
Bone mineral density improvement by Vitamin D plus fluoride is augmented by laser acupuncture – RCT March 2023 22 Mar, 2023
Perhaps higher risk of fracture if low BMD plus low vitamin D – July 2022 08 Jul, 2022
Exercise improves bone strength (good), but not bone mineral density (can be measured) – RCT Oct 2021 08 Oct, 2021
Bone Mineral Density increased by Resveratrol (which activates the Vitamin D Receptor) – RCT Nov 2020 17 Feb, 2021
Low bone mineral density is inversely associated with both Vitamin D and Resistin (resistance to insulin) 15 Jan, 2021
Breast Cancer chemo reduces Bone Mineral Density, injecting Vitamin D increases it – Sept 2019 07 Sep, 2019
Bone mineral density somewhat better with 3750 IU vs 600 IU Vitamin D (1 year, with Calcium) – RCT March 2017 10 Mar, 2017
Low bone mineral density of male children is associated with low BMD of parents – Oct 2016 18 Oct, 2016
Osteoporosis vitamin D workshop - but still test BMD first - Oct 2010 19 Jan, 2016
Bone strength (more accurate than BMD) is inversely associated with vitamin D level – May 2015 30 May, 2015
Long bone fracture – prediction by low vitamin D is better than low BMD – Sept 2014 16 May, 2015
Hypothesis: increased bone mineral density needs protein, Ca, Mg, Vitamin D and K 28 Oct, 2014
Increasing bone mineral density increases breast cancer by at least 2X – Aug 2012 26 Oct, 2014
600,000 IU intramuscular D3 helped BMD after pancreatic surgery – June 2010 24 Jan, 2014
BMD associated with free and bioavailable vitamin D – March 2011 06 Jan, 2014
Low vitamin D, not low BMD, associated with both breaking hip and upper body bone in a fall – Oct 2013 05 Nov, 2013
Acute Multiple Sclerosis relapse associated with low bone mineral density (low vitamin D) – Oct 2013 12 Oct, 2013
Vitamin K2 from natto improved bone mineral density – March 2011 11 Oct, 2013
Working other than dayshift reduces vitamin D levels and Bone Mineral Density and increases bone pain – Aug 2013 22 Aug, 2013
Low vitamin D associated with 5.5X increased risk of low bone mineral density – March 2013 22 Aug, 2013
Hypothesis: Not vitamin D deficient if have normal PTH and BMD – May 2013 01 Jun, 2013
Vitamin D did not increase BMD among some ballet dancers – March 2012 28 Mar, 2012
9 minutes a day of sun improved BMD Parkinsons disease patients – Jan 2011 01 Jun, 2011
Reduced vitamin D and BMD and Neurological Conditions – April 2011 05 May, 2011
BMD improved with 800 mg Calcium, 400 IU of vitamin D, and 100 ug of vitamin K – April 2011 04 Apr, 2011
Low BMD among teaching doctors in India - July 2010 09 Jul, 2010

4 possible ways the laser acupuncture might work

  1. Energizes the mitocondria
  2. Increases Vitamin D
  3. Increases Magnesium
  4. Increases Nitric Oxide
Laser Acupuncture: A Concise Review - June 2021

 Download the PDF from VitaminDWiki

Study References
  1. Siris E, Adler R, Bilezikian J, et al. The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working Group. OsteoporosInt 2014;25:1439–1443. doi: 10.1007/s00198-014-2655-z - DOI
  2. Nuti R, Brandi ML, Checchia G, Di Munno O, Dominguez L, Falaschi P, Fiore CE, Iolascon G, Maggi S, Michieli R, Migliaccio S, Minisola S, Rossini M, Sessa G, Tarantino U, Toselli A, Isaia GC. Guidelines for the management of osteoporosis and fragility fractures. Intern Emerg Med. 2019;14:85–102. doi: 10.1007/s11739-018-1874-2 - DOI
  3. Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res 2007;22:465–475. doi: 10.1359/jbmr.061113 - DOI
  4. Edwards BJ, Song J, Dunlop DD, Fink HA, Cauley JA. Functional decline after incident wrist fractures—study of osteoporotic fractures: prospective cohort study. BMJ 2010;341:c3324. doi: 10.1136/bmj.c3324 - DOI
  5. Cosman F, de Beur SJ, LeBoff MS, et al. Clinician's guide to prevention and treatment of osteoporosis. Osteoporos Int 2014;25:2359–2381. doi: 10.1007/s00198-014-2794-2 - DOI
  6. Rozental TD, Branas CC, Bozentka DJ, Beredjiklian PK. Survival among elderly participants after fractures of the distal radius. J Hand Surg 2002;27A:948–952. doi: 10.1053/jhsu.2002.36995 - DOI
  7. Crandall CJ, Hovey KM, Cauley JA, et al. Wrist fracture and risk of subsequent fracture: findings from the Women's Health Initiative Study. J Bone Miner Res 2015;30:2086–2095. doi: 10.1002/jbmr.2559 - DOI
  8. Abdelmohsen AM. Comparison of central and peripheral bone mineral density measurements in postmenopausal women. J Chiropr Med 2017;16:199–203. doi: 10.1016/j.jcm.2017.08.001. PMID: 29097949; PMCID: PMC5659807 - DOI
  9. Nelson HD. Menopause. Lancet 2008;371:760–770. doi: 10.1016/s0140-6736(08)60346-3 - DOI
  10. Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from The Women's Health Initiative randomized controlled trial. JAMA 2002;288:321–333. doi: 10.1001/jama.288.3.321 - DOI
  11. Kling JM, Clarke BL, Sandhu NP. Osteoporosis prevention, screening, and treatment: a review. J Womens Health 2014;23:563–572. doi: 10.1089/jwh.2013.4611 - DOI
  12. Whittaker P. Laser acupuncture: past, present, and future. Las Med Scie 2004;19:69–80. doi: 10.1007/s10103-004-0296-8 - DOI
  13. Baxter GD, Bleakley C, McDonough S. Clinical effectiveness of laser acupuncture: a systematic review. J Acupunct Meridian Stud 2008;1:65–82. doi: 10.1016/S2005-2901(09)60026-1 - DOI
  14. Mason S, Tovey P, Long AF. Evaluating complementary medicine: methodological challenges of randomised controlled trials. BMJ 2002;325:832–834. doi: 10.1136/bmj.325.7368.832
  15. Sunay D, Ozdiken M, Arslan H, Seven A, Aral Y. The effect of acupuncture on postmenopausal symptoms and reproductive hormones: a sham controlled clinical trial. Acupunct Med 2011;29:27–31. doi: 10.1136/aim.2010.003285 - DOI
  16. Zhou ZH, Wang NQ, Pan FF, Wu ZH, Dai XY. Clinical observation on combined acupuncture and medication for osteoporosis in postmenopausal women. J AcupunctTuinaSci 2011;9:370–375. (In Chinese). doi: 10.1007/s11726-011-0554-9 - DOI
  17. World Health Organization (WHO). Prevention and management of osteoporosis. World Health Organ Tech Rep Ser 2003;921:1–164.back cover. PMID: 15293701
  18. Klimek L, Bergmann KC, Biedermann T, et al. Visual analogue scales (VAS): Measuring instruments for the documentation of symptoms and therapy monitoring in cases of allergic rhinitis in everyday health care: position paper of the German Society of Allergology (AeDA) and the German Society of Allergy and Clinical Immunology (DGAKI), ENT Section, in collaboration with the working group on Clinical Immunology, Allergology and Environmental Medicine of the German Society of Otorhinolaryngology, Head and Neck Surgery (DGHNOKHC). Allergo J Int 2017;26:16–24. doi: 10.1007/s40629-016-0006-7 - DOI
  19. He W, Litscher G, Jing XH, et al. Effectiveness of interstitial laser acupuncture depends upon dosage: experimental results from electrocardiographic and electrocorticographic recordings. Evid Based Complement Alternat Med 2013;2013:934783. doi: 10.1155/2013/934783. PMID: 24348729; PMCID: PMC3853036 - DOI
  20. Jing C. Anatomical Atlas of Chinese Acupuncture Points: The Cooperative Group of Shandong Medical College and Shandong College of Traditional Chinese Medicine. 3rd ed,. Jinan, China: Shandong Science and Technology Press; 1990:14–52.
  21. Hassan E, EL-Badry S, Yousef A, Hamada H, Mostafa M. Effect of laser acupuncture on lumbar bone mineral density and back pain in postmenopausal women with osteoporosis: a randomized controlled trial. FizjoterapiaPolska 2019;19:116–121.
  22. Lai YH, Fang TC. The pleiotropic effect of vitamin D. ISRN Nephrol 2013;2013:898125. doi: 10.5402/2013/898125 - DOI
  23. Woolf CJ. What to call the amplification of nociceptive signals in the central nervous system that contribute to widespread pain? Pain 2014;155:1911–1912. doi: 10.1016/j.pain.2014.07.021 - DOI
  24. Mascarenhas C, Mobarhan S. Hypovitainosis D–induced pain. Nutr Rev 2004;62:354–359. doi: 10.1111/j.1753-4887.2004.tb00061.x - DOI
  25. Schleithoff SS, Zittermann A, Tenderich G, Berthold HK, Stehle P, Koerfer R. Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial. Am J ClinNutr 2006;83:754–759. doi: 10.1093/ajcn/83.4.754 - DOI
  26. Yan GM, Huang YQ, Cao H, Wu J, Jiang N, Cao XN. Association of breastfeeding and postmenopausal osteoporosis in Chinese women: a community-based retrospective study. BMC Womens Health 2019;19:110. doi: 10.1186/s12905-019-0808-0 - DOI
  27. Chon S, Koh Y, Heo J, et al. Effects of vitamin D deficiency and daily calcium intake on bone mineral density and osteoporosis in Korean postmenopausal woman. Obstet Gynecol Sci 2017;60:53–62. doi: 10.5468/ogs.2017.60.1.53 - DOI
  28. Weaver C, Alexander D, Boushey C, et al. Calcium plus vitamin D supplementation and risk of fractures: an updated meta-analysis from the National Osteoporosis Foundation. Osteoporos Int 2016;27:367–376. doi: 10.1007/s00198-015-3386-5 - DOI
  29. Goyal V, Agrawal M. Effect of supplementation of vitamin D and calcium on patients suffering from chronic non-specific musculoskeletal pain: a pre-post study. J Family Med Prim Care 2021;10:1839–1844. doi: 10.4103/jfmpc.jfmpc_1699_20 - DOI
  30. Guo X, Liu MQ, Man HC, et al. laser acupuncture and prevention of bone loss in tail-suspended rats. Aviat Space Environ Med 2010;81:914–918. doi: 10.3357/asem.2737.2010 - DOI
  31. Yeom M, Kim SH, Lee B, et al. Effects of laser acupuncture on longitudinal bone growth in adolescent rats. Evid Based Complement Alternat Med 2013;2013:424587. doi: 10.1155/2013/424587
  32. Cai G, Li J, Xue Y, Li G, Wu M, Li P. Warm needling combined with element calcium for postmenopausal osteoporosis. Zhongguo Zhen Jiu 2015;35:881–884.Chinese. PMID: 26721135
  33. Shi N, Zhao C, Fang C, Zhang D, Zhou Z, Ouyang G. Effects of acupoint catgut embedding on the postmenopausal osteoporosis patients and related mechanism. Am J Transl Res 2021;13:1789–1798. PMID: 33841703; PMCID: PMC8014430
  34. Ren ZQ, Wang YF, Ao GF, et al. Overall adjustment acupuncture for postmenopausal osteoporosis (PMOP): a study protocol for a randomized sham-controlled trial. Trials 2020;21:465. doi: 10.1186/s13063-020-04435-7
  35. Xiangling H. Effect of acupuncture on bone mineral density and serum estrogen in postmenopausal osteoporosis patients. Hunan J Tradit Chin se Med 2016;32:86–87. [Google Scholar]
  36. Donghao G, Deqiang C, Guoqing T, Zhanwang X. Investigating the development of bone marrow adiposis in primary osteoporosis based on signal crosslinking. Chin J Osteoporos 2019;25:1176–1180. [Google Scholar]
  37. Fan H, Ji F, Lin Y, et al. Electroacupuncture stimulation at CV4 prevents ovariectomy induced osteoporosis in rats via Wnt ß catenin signaling. Mol Med Rep 2016;13:2485–2491. doi: 10.3892/mmr.2016.4849 - DOI
  38. Zhou J, Chen S, Guo H. Electroacupuncture prevents ovariectomy-induced osteoporosis in rats: a randomized controlled trial. Acupunct Med 2012;30:37–43. doi: 10.1136/acupmed-2011-010114 - DOI
  39. Zheng X, Wu G, Nie Y, Lin YL. Electroacupuncture at the governor vessel and bladder meridian acupoints improves postmenopausal osteoporosis through osteoprotegerin/RANKL/RANK and Wnt/ß-catenin signaling pathways. Exp Ther Med 2015;10:541–548. doi: 10.3892/etm.2015.2553 - DOI
  40. He J, Yang L, Qing Y, He C. Effects of electroacupuncture on bone mineral density, oestradiol level and osteoprotegerin ligand expression in ovariectomized rabbits. Acupunct Med 2014;32:37–42. doi: 10.1136/acupmed-2012-010271 - DOI
  41. Zhu CT, Li T, Zhang P, Zou M, Guo Q, Qu XW. Beneficial effects of low-level laser irradiation on senile osteoporosis in rats. Eur Rev Med Pharmacol Sci 2017;21:5230–5238. doi: 10.26355/eurrev_201711_13846 - DOI
  42. Amid R, Kadkhodazadeh M, Ahsaie MG, Hakakzadeh A. Effect of low level laser therapy on proliferation and differentiation of the cells contributing in bone regeneration. J Lasers Med Sci 2014;5:163–170. PMID: 25653816; PMCID: PMC4281990
  43. Saad A, El Yamany M, Abbas O, Yehia M. Possible role of ++low level laser therapy on bone turnover__ in ovariectomized rats. Endocr Regul 2010;44:155–163. doi: 10.4149/endo_2010_04_155 - DOI
  44. Xu M, Deng T, Mo F, et al. Low-intensity pulsed laser irradiation affects RANKL and OPG mRNA expression in rat calvarial cells. Photomed Laser Surg 2009;27:309–315. doi: 10.1089/pho.2008.2283 - DOI
  45. Glazov G, Yelland M, Emery J. Low-dose laser acupuncture for non-specific chronic low back pain: a double-blind randomised controlled trial. Acupunct Med 2014;32:116–123. doi: 10.1136/acupmed-2013-010456 - DOI
  46. Schiller J, Korallus C, Bethge M, et al. Effects of acupuncture on quality of life and pain in patients with osteoporosis—a pilot randomized controlled trial. Arch Osteoporos 2016;11:34. doi: 10.1007/s11657-016-0288-x - DOI
  47. Luo D, Liu Y, Wu Y, et al. Warm needle acupuncture in primary osteoporosis management: a systematic review and meta-analysis. Acupunct Med 2018;36:215–221. doi: 10.1136/acupmed-2016-011227 - DOI
  48. Cai GW, Li J, Xu XJ, et al. Clinical research on warm acupuncture therapy for pain in postmenopausal osteoporosis. Zhongguo Zhen Jiu 2014;34:25–27
  49. Hashmi JT, Huang YY, Osmani BZ, et al. Role of low-level laser therapy in neurorehabilitation. PMR 2010;212(suppl 2):S292–S305. doi: 10.1016/j.pmrj.2010.10.013 - DOI

Bone mineral density improvement by Vitamin D plus fluoride is augmented by laser acupuncture – RCT March 2023        
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