- 40+ VitaminDWiki pages have COIMBRA in the title
- Autoimmune Diseases and high-dose Vitamin D (Coimbra protocol) - 60 minute video Oct 2022
- Interview with Dr. Menendez - Coimbra Protocol and Vitamin D 66 minutes Sept 2024
- Coimbra Protocol: Multiple Sclerosis & Tumor Diseases July 2024 29 minutes
- The Coimbra Protocols of Vitamin D in Managing Autoimmune Diseases, What is Vitamin D Resistance? 23 minutes Jan 2025
- VitaminDwiki – High-Dose contains:
40+ VitaminDWiki pages have COIMBRA in the title
This list is automatically updated
Autoimmune Diseases and high-dose Vitamin D (Coimbra protocol) - 60 minute video Oct 2022
Dr. Baker YouTube
01:39 Experience with Coimbra protocol
02:17 Medical background; neurology
04:49 Conventional medicine is pharmacological intervention
07:18 Field of neurology is conservative
08:12 Large doses of vitamin D and calcium metabolism
11:56 Ataxia treatment
12:59 Resignation from hospital and working with autoimmune patients
14:32 Medical community reception of Comibra protocol
15:49 Vitamin D in evolution
16:45 Vitamin D and hormones
18:15 Different branches of metabolism
19:26 Plant-based vs. animal-based vitamin D
19:43 Are people with autoimmune disease vitamin D-resistant?
21:57 German scientist studying vitamin D in Finland
24:41 Greenland Eskimos and rickets
25:32 Vitamin D receptor protein
29:36 Vitamin D role in body
31:30 Blocking vitamin D receptors; Lyme disease
34:37 Vitamin K and vitamin D
37:54 Vitamin D and parathyroid hormones
40:55 Kidneys and hypercalcemia in Coimbra protocol
43:20 Adapting to problems
45:56 Vitamin D for other autoimmune diseases
46:35 Crohn's and ulcerative colitis; lupus erythematosus; psoriasis
49:04 Untreated vitamin D resistance and chance of getting an autoimmune disease
49:34 Making lifestyle changes
50:44 Carnivore diet for patients
53:28 Dangers of high dose vitamin D
55:13 Signs of vitamin D overdose
56:05 Don’t try this at home
58:01 Abnormal range serum calcium
Interview with Dr. Menendez - Coimbra Protocol and Vitamin D 66 minutes Sept 2024
- (01:13) Dr. Sergio Menendez is a specialist in autoimmune diseases who studied medicine in Havana, completed his PhD in neurological science in Brazil, and has treated over 4,500 patients with the Coimbra Protocol since 2012.
- (09:28) The Coimbra Protocol was created by neurologist Dr. Coimbra in 2002 and is based on high doses of vitamin D to control autoimmune diseases, with approximately 90% of patients experiencing disease remission.
- (10:15) Autoimmune diseases occur when the immune system mistakenly attacks the body's own tissues, producing autoantibodies that cause inflammation and tissue damage in specific regions (examples: multiple sclerosis, rheumatoid arthritis, lupus).
- (18:23) Dr. Coimbra discovered that patients with autoimmune diseases have resistance to converting inactive vitamin D to active vitamin D, requiring much higher doses than typically prescribed to receive therapeutic benefits.
- (22:40) Vitamin D has three key functions in controlling autoimmune diseases: increasing defense against pathogens, improving immune tolerance, and blocking autoimmune inflammatory responses.
- (24:51) The main potential toxicity concern with high-dose vitamin D is excessive calcium absorption, which can damage kidneys. Patients must follow dietary restrictions (avoiding dairy products, certain seeds) and drink plenty of water to maintain calcium balance.
- (36:42) Symptoms of excessive calcium include persistent thirst, nausea, vomiting, constipation, stomach pain, and loss of appetite. If these occur, patients should stop the protocol and contact their doctor.
- (42:54) The protocol requires ongoing supervision by doctors specifically trained in the Coimbra Protocol through blood and urine tests. Patients can find qualified doctors worldwide (though they are limited in France).
- (45:02) Treatment duration varies, as autoimmune diseases are chronic. Some patients need high doses for many years while others can eventually reduce to maintenance doses of 10,000 IU daily.
- (59:28) Beyond the protocol, patients should manage stress levels, get adequate rest, maintain physical activity, and follow a healthy lifestyle to reduce autoimmune disease risk factors.
Coimbra Protocol: Multiple Sclerosis & Tumor Diseases July 2024 29 minutes
- (00:00-00:45) Introduction to the "Coimbra Protocol," a revolutionary approach developed by Professor Coimbra, a neurologist at the University of St. Paul.
- (01:27-03:12) The protocol focuses on vitamin D's role in autoimmune diseases, particularly MS. Vitamin D affects 249 gene expressions per cell and controls hundreds of thousands of immune reactions, but modern lifestyles limit our sun exposure and vitamin D production.
- (04:07-05:37) Professor Coimbra discovered that increasing vitamin D dosage gradually (from 5,000 to 40,000+ units) can help MS patients by saturating cells with vitamin D, as people with autoimmune diseases have vitamin D receptor issues.
- (06:59-08:22) The protocol requires medical supervision and should not be attempted by laypeople. It involves careful monitoring and personalized dosing, which has reportedly helped many MS patients regain mobility.
- (09:18-10:49) Following the protocol requires dietary changes, particularly limiting calcium intake from dairy products, as vitamin D increases calcium absorption, which could potentially cause kidney issues if not monitored properly.
- (12:30-14:18) The protocol has shown benefits for various autoimmune conditions beyond MS, including psoriasis, vitiligo, and other neurodegenerative diseases, with dosages reaching up to 300,000 units per day in some cases.
- (16:42-19:26) Despite numerous studies on vitamin D's importance, there's a "knowledge resistance" in mainstream medicine. Many doctors don't routinely check vitamin D levels, though it was once common practice to supplement children.
- (20:10-22:37) Vitamin D supplementation can have dramatic effects on other conditions like depression. Dr. Wiechel recommends measuring vitamin D levels in March and October and supplementing accordingly.
- (23:26-25:41) Vitamin D acts like "police" in the body, helping natural killer cells recognize and eliminate cancer cells. Studies show 30% fewer tumors in people with adequate vitamin D levels.
- (26:29-28:19) Conclusion encourages viewers to check their vitamin D levels and consider the Coimbra Protocol if dealing with MS or autoimmune conditions, emphasizing the importance of expert supervision.
The Coimbra Protocols of Vitamin D in Managing Autoimmune Diseases, What is Vitamin D Resistance? 23 minutes Jan 2025
- (00:00) The Coimbra Protocol uses therapeutic doses of vitamin D to manage various autoimmune conditions including lupus, rheumatoid arthritis, IBS, psoriasis, multiple sclerosis, and type 1 diabetes.
- (01:19) Autoimmune disorders involve either immunodeficiency (immune system too weak) or hypersensitivity (immune system misdirected), with 60-80 chronic inflammatory diseases affecting 5-8% of the US population, with 75% of cases occurring in women.
- (03:21) Autoimmunity can affect any organ system and has been dramatically increasing since the 1950s, with environmental factors, genetic predisposition, and vitamin D deficiency as major contributing factors.
- (09:52) A case study from Finland showed an inverse relationship between recommended vitamin D intake and type 1 diabetes incidence - as vitamin D recommendations decreased from 4,500 IU (1964) to 400 IU (1992), diabetes cases significantly increased.
- (11:39) Vitamin D modulates immune response by promoting a shift from Th1 to Th2, suppressing inflammatory Th17 reactions, and facilitating T-regulatory cells that balance immune response.
- (13:39) Vitamin D deficiency contributes to gut dysbiosis and leaky gut, which can trigger autoimmune responses; proper vitamin D supplementation helps reduce inflammation and strengthen gut barrier function.
- (16:39) Research shows that doubling serum vitamin D concentration decreases multiple sclerosis exacerbation rates by 27%, with similar benefits demonstrated for psoriasis, vitiligo, rheumatoid arthritis, and lupus.
- (19:54) Many autoimmune patients have "vitamin D resistance" due to genetic polymorphisms, requiring much higher therapeutic doses than typically recommended to achieve immunomodulatory effects.
- (21:43) Case studies show lesions in multiple sclerosis patients completely disappearing after high-dose vitamin D therapy, with Dr. Coimbra describing vitamin D deficiency as "a disaster for the immune system."
VitaminDwiki – High-Dose contains:
High Dose = the on-going use of >5,000 IU (daily average)
Dosing frequency: 1 per day to 1 per 17 days is best, however some studies use monthly dosing
High Dose has been used millions of times - safely and effectively
High Dose for more than 6 months should include the adjustment of co-factors
>100,000 daily can be toxic in 3 weeks if cofactors are not adjusted
Can be via injections
High dose is not the same as a Loading Dose (bolus)
- A Loading Dose is a high-dose typically completed in less than 30 days
See also
Is 50 ng of vitamin D too high, just right, or not enough
Vitamin D: Bolus is Bogus (if more than 17 days between oral doses) – Oct 2021