Sunlight and Vitamin D: A global perspective for health
Matthias Wacker, Michael F. Holick
Dermato-Ednorcrinology Vol5 #1
Vitamin D is the sunshine vitamin that has been produced on this earth for more than 500 million years. During exposure to sunlight 7-dehydrocholesterol in the skin absorbs UV B radiation and is converted to previtamin D3 which in turn isomerizes into vitamin D3. Previtamin D3 and vitamin D3 also absorb UV B radiation and are converted into a variety of photoproducts some of which have unique biologic properties. Sun induced vitamin D synthesis is greatly influenced by season, time of day, latitude, altitude, air pollution, skin pigmentation, sunscreen use, passing through glass and plastic, and aging. Vitamin D is metabolized sequentially in the liver and kidneys into 25-hydroxyvitamin D which is a major circulating form and 1,25-dihydroxyvitamin D which is the biologically active form respectively. 1,25-dihydroxyvitamin D plays an important role in regulating calcium and phosphate metabolism for maintenance of metabolic functions and for skeletal health. Most cells and organs in the body have a vitamin D receptor and many cells and organs are able to produce 1,25-dihydroxyvitamin D. As a result 1,25-dihydroxyvitamin D influences a large number of biologic pathways which may help explain association studies relating vitamin D deficiency and living at higher latitudes with increased risk for many chronic diseases including autoimmune diseases, some cancers, cardiovascular disease, infectious disease, schizophrenia and type 2 diabetes. A three-part strategy of increasing food fortification programs with vitamin D, sensible sun exposure recommendations and encouraging ingestion of a vitamin D supplement when needed should be implemented to prevent global vitamin D deficiency and its negative health consequences.
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58+ VitaminDWiki pages have HOLICK in the title
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Items found: 59
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Vitamin D proven to help in many ways, but little change in recommendations - Holick Jan 2025 |
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28 Jan, 2025 |
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Vitamin D gets trapped in fat cells - improved understanding - Holick Jan 2025 |
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02 Jan, 2025 |
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Revisiting Vitamin D Guidelines – Holick Oct 2024 |
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15 Nov, 2024 |
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Vitamin D interview and transcript - Dr. Holick Aug 2024 |
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06 Sep, 2024 |
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Dr. Holick interview with transcript - May 2024 |
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05 May, 2024 |
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Podcast by Dr. Holick on vitamin D - Feb 2011 |
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05 May, 2024 |
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Prostate Cancer - interview of Dr. Holick by Baggerly - video and transcript Jan 2024 |
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05 May, 2024 |
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Should You Take A Vitamin D Supplement - Dr Holick transcript Oct 2022 |
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28 Nov, 2023 |
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Vitamin D: 100 year anniversary of discovery – Holick Jan 2023 |
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23 Jan, 2023 |
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Vitamin D and neurocognitive function – Holick April 2014 |
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21 Oct, 2022 |
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Vitamin D and neurocognitive function – Holick Oct 2022 |
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21 Oct, 2022 |
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How Sensible Sun Exposure Benefits Your Health -Holick interview May 2022 |
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30 May, 2022 |
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UV, sunshine, and vitamin D (87 charts) - Holick March 2013 |
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11 Jan, 2022 |
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Vitamin D and COVID-19: a narrative review - Holick - Jan 4, 2022 |
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10 Jan, 2022 |
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Low Vitamin D in infants - video interview of Dr. Holick - May 2017 |
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11 Dec, 2021 |
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Hospital has banned Dr. Holick due to testifying in cases of infants with broken bones- August, 2021 |
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03 Aug, 2021 |
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Vitamin D Is Not as Toxic as Was Once Thought – Holick May 2015 |
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20 Mar, 2021 |
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Vitamin D, Zinc, etc. look promising for COVID-19 (Holick) - Jan 25, 2021 |
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28 Jan, 2021 |
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Call to action: Vitamin D to prevent of treat hip fracture (50,000 weekly for 8 weeks, then bi-weekly) – Holick July 2020 |
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11 Dec, 2020 |
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Rate of COVID-19 test positive is 40 pcnt lower if high vitamin D (192,000 people) - Holick Sept 2020 |
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17 Sep, 2020 |
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Immunologic Effects of Vitamin D on Human Health and Disease - Holick July 2020 |
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15 Jul, 2020 |
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The vitamin D deficiency pandemic – Holick May 2017 |
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21 Jan, 2020 |
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Call to action – more Vitamin D for pregnancies, loading doses are OK – Holick Aug 2019 |
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25 Jun, 2019 |
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Diagnosis and treatment of osteopenia – Holick 2010 |
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10 Dec, 2018 |
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Photobiology of Vitamin D – free chapter in book – Holick 2010 |
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17 Nov, 2018 |
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Kaiser Health News wrote a damning article about Dr. Holick and Vitamin D, NYT published it – Aug 2018 |
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20 Aug, 2018 |
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Vitamin D - at least 4,000 IU to achieve 40-60 ng and reduce risk of early death – Holick June 2018 |
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04 Jun, 2018 |
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Role of Vitamin D in the Pathogenesis of Diabetes – Holick July 2017 |
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16 Jul, 2017 |
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The risks and benefits of sun exposure – Holick Oct 2016 |
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05 Jan, 2017 |
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Vitamin D presentation by Dr. Holick Spring 2012 |
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08 Mar, 2016 |
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Holick interview by Mercola on Vitamin D – Dec 2015 |
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17 Jan, 2016 |
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Major review of Vitamin D – Holick Feb 2013 |
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27 Dec, 2015 |
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Vitamin D Global Perspective - Holick June 2013 |
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27 Dec, 2015 |
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Dr. Holick video on vitamin D - March 2013 |
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27 Dec, 2015 |
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Vitamin D from 1940 and into the future – Holick video Nov 2013 |
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28 Nov, 2015 |
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Vitamin D review – Holick Jan 2013 |
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24 Sep, 2015 |
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Go ahead, soak up some sun (but don’t burn) – Holick July 2015 |
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01 Aug, 2015 |
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Chicago Sun Times on vitamin D: Depression, chest pain, fibromyalgia, Holick, 3000 IU without test - May 2010 |
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15 Jul, 2015 |
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Chicago Times on vitamin D: Depression, chest pain, fibromyalgia, Holick, 3000 IU without test - May 2010 |
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15 Jul, 2015 |
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Live Longer with Vitamin D - Holick March 2015 |
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17 May, 2015 |
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Sunlight and Your Health: An EnLIGHTening Perspective - Holick Video Dec 2014 |
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14 Mar, 2015 |
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Less sun means more disease -Grant, Holick, Cannell, et al Feb 2015 |
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05 Mar, 2015 |
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Cancer, Sunlight, and Vitamin D - Holick Oct 2014 |
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06 Oct, 2014 |
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Environmental factors that influence the cutaneous production of vitamin D – Holick 1995 |
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06 Jan, 2014 |
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If You're Low in This Nutrient, It Doubles Your Odds of Many Cancers– Interview Dr. Holick Oct 2013 |
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23 Dec, 2013 |
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Patent application for a skin cream which enhances production of vitamin D – Holick July 2013 |
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24 Nov, 2013 |
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Vitamin D update – Holick Sept 2013 |
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11 Nov, 2013 |
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Vitamin D, Sunlight and Cancer Connection – Holick Jan 2013 |
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11 Aug, 2013 |
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Vitamin D encyc. - 2nd edition, Holick - April 2013 |
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02 Mar, 2013 |
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Major review of Vitamin D – Holick 2013 part II |
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08 Feb, 2013 |
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Vitamin D: A D-Lightful Vitamin for Health – Holick Dec 2012 |
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07 Jan, 2013 |
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Evidence for vitamin D – Holick June 2012 |
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23 Nov, 2012 |
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VITAMIN D: A D-LIGHTFUL SOLUTION FOR GOOD HEALTH – Holick 2012 |
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30 Oct, 2012 |
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Michael Holick – reduce health care costs 25 percent – interview Sept 2010 |
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07 Oct, 2012 |
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High Prevalence of Vitamin D Inadequacy - Holick Mayo Clinic 2006 |
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14 May, 2012 |
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Professional book on Vitamin D - Editor Holick 2010 |
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27 Aug, 2011 |
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Vitamin D Holick – Jan 2011 |
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29 Mar, 2011 |
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Vitamin D is essential to the modern indoor lifestyle – interview Holick Oct 2010 |
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09 Oct, 2010 |
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Interview of pioneer in Vitamin D research - Holick LEF Sept 2010 |
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08 Sep, 2010 |
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Short url = http://is.gd/Holick32013